When a therapist calculates PVR at 300 dynes/sec/cm^-5, what underlying problem should they suspect?

A calculated PVR (pulmonary vascular resistance) of 300 dynes/sec/cm^-5 indicates an elevated resistance within the pulmonary circulation, which is often linked to conditions such as hypoxia or pulmonary hypertension.

In the context of pulmonary hypertension, the increased resistance is caused by various factors that may lead to abnormal narrowing or obstruction in the pulmonary vessels, which hinders blood flow and increases the workload on the right side of the heart. Conditions leading to hypoxia, such as chronic obstructive pulmonary disease (COPD) or interstitial lung disease, can also contribute to elevated PVR as the body tries to compensate for reduced oxygen availability by constricting pulmonary blood vessels.

Thus, elevated PVR is a hallmark finding that prompts suspicion of these underlying issues in the context of respiratory and cardiovascular assessments. Recognizing and addressing the causes of elevated PVR is critical in management, as it can guide treatment aimed at alleviating symptoms and improving oxygenation and hemodynamic stability.